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Toshiaki Sato Selected Research

KT 5720

7/20086-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2-(1H)quinolinone (cilostazol), a phosphodiesterase type 3 inhibitor, reduces infarct size via activation of mitochondrial Ca2+-activated K+ channels in rabbit hearts.
1/2008Infarct size limitation by adrenomedullin: protein kinase A but not PI3-kinase is linked to mitochondrial KCa channels.

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Toshiaki Sato Research Topics

Disease

7Atrial Fibrillation
10/2020 - 05/2004
6Ischemia
03/2009 - 02/2003
5Infarction (Infarctions)
03/2009 - 09/2003
5Reperfusion Injury
03/2009 - 02/2003
4Hypertension (High Blood Pressure)
04/2011 - 10/2002
4Myocardial Ischemia (Ischemic Heart Diseases)
02/2009 - 12/2004
4Atrial Remodeling
05/2004 - 05/2002
3Ventricular Tachycardia
01/2019 - 06/2009
3Heart Diseases (Heart Disease)
09/2012 - 12/2003
3Long QT Syndrome
09/2012 - 04/2010
2Hypothermia
05/2012 - 04/2010
2Cardiac Sudden Death (Sudden Cardiac Arrest)
04/2010 - 12/2003
2Heart Failure
05/2009 - 09/2008
2Hypoxia (Hypoxemia)
06/2008 - 09/2003
2Overweight
10/2002 - 10/2002
1Pericardial Effusion
10/2020
1Cardiac Tamponade
10/2020
1Cardiac Arrhythmias (Arrythmia)
01/2019
1Ventricular Premature Complexes (Premature Ventricular Contraction)
01/2019
1Arteriovenous Fistula
09/2018
1Atrioventricular Block
08/2017
1Atrioventricular Nodal Reentry Tachycardia (AV Nodal Reentrant Tachycardia)
08/2017
1Seasonal Allergic Rhinitis (Hay Fever)
08/2016
1Thrombosis (Thrombus)
06/2016
1Hemolysis
08/2015
1Body Weight (Weight, Body)
01/2015
1Cardiovascular Diseases (Cardiovascular Disease)
09/2013
1Heart Arrest (Cardiac Arrest)
05/2012
1Coma (Comas)
05/2012
1Torsades de Pointes (Torsade de Pointes)
04/2010
1Brugada Syndrome
01/2010
1Sudden Death
06/2009
1Bradycardia
06/2009
1Cardiomyopathies (Cardiomyopathy)
09/2008
1Cardiomegaly (Heart Hypertrophy)
02/2008
1Hypotension (Low Blood Pressure)
07/2005
1Fibrosis (Cirrhosis)
06/2004

Drug/Important Bio-Agent (IBA)

4Adenosine Triphosphate (ATP)IBA
06/2008 - 02/2003
3Pharmaceutical PreparationsIBA
04/2010 - 12/2004
3triphenyltetrazoliumIBA
02/2009 - 01/2008
2Ion Channels (Ion Channel)IBA
09/2012 - 03/2009
2Bepridil (Vascor)FDA Link
06/2009 - 01/2006
2mitochondrial K(ATP) channelIBA
03/2009 - 02/2003
2AdrenomedullinIBA
03/2009 - 01/2008
2KT 5720IBA
07/2008 - 01/2008
2Verapamil (Calan)FDA LinkGeneric
05/2004 - 05/2002
2LeptinIBA
10/2002 - 10/2002
1Polyvinyl Chloride (PVC)IBA
01/2019
1Biological ProductsIBA
08/2016
1PowdersIBA
08/2016
1Warfarin (Coumadin)FDA LinkGeneric
06/2016
1apixabanIBA
06/2016
1DabigatranFDA Link
06/2016
1Factor Xa InhibitorsIBA
06/2016
1AnticoagulantsIBA
06/2016
1HDL CholesterolIBA
01/2015
1LDL CholesterolIBA
01/2015
1omega-Chloroacetophenone (Mace)IBA
09/2013
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
04/2011
1candesartanIBA
04/2011
1Angiotensin Receptor AntagonistsIBA
04/2011
1Amlodipine (Norvasc)FDA LinkGeneric
04/2011
1pilsicainideIBA
01/2010
1Sodium Channel BlockersIBA
01/2010
1TamoxifenFDA LinkGeneric
05/2009
1BradykininIBA
03/2009
1Adenosine (Adenocard)FDA LinkGeneric
03/2009
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
02/2009
1glimepiride (Amarel)FDA LinkGeneric
02/2009
12- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA
02/2009
1Brain Natriuretic Peptide (Natrecor)FDA Link
09/2008
1Calcium-Activated Potassium Channels (Calcium-Activated Potassium Channel)IBA
07/2008
1Milrinone (Primacor)FDA LinkGeneric
07/2008
1protein kinase modulatorIBA
07/2008
1Carboxylic AcidsIBA
07/2008
1QuinolonesIBA
07/2008
1Cilostazol (Pletal)FDA LinkGeneric
07/2008
1EstersIBA
07/2008
1FlavoproteinsIBA
07/2008
1Phosphodiesterase 3 InhibitorsIBA
07/2008
1paxillineIBA
07/2008
1Glucose (Dextrose)FDA LinkGeneric
06/2008
1Angiotensin IIIBA
02/2008
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
02/2008
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
01/2008
1Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
01/2008
1Atrial Natriuretic Factor (ANF)IBA
07/2005
1Prostaglandins EIBA
05/2005
1Epoprostenol (Prostacyclin)FDA LinkGeneric
05/2005
14- (7- ((2- 3- chloro- 2- thienyl)- 1- methyl- propylamino)- 3H- imidazo(4,5- b)pyridyl- 3- yl)cyclopentane carboxamideIBA
12/2004
1Transforming Growth Factor beta1 (TGF beta 1)IBA
06/2004
1CalciumIBA
05/2004
1Anti-Arrhythmia AgentsIBA
12/2003

Therapy/Procedure

5Therapeutics
04/2015 - 01/2010
4Catheter Ablation
10/2020 - 04/2015
2Catheters
01/2019 - 09/2018
1Renal Dialysis (Hemodialysis)
09/2018
1Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
08/2015
1Induced Hypothermia
05/2012
1Cardiac Resynchronization Therapy
09/2008